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1

Individuals with familial hypercholesterolemia and cardiovascular events have higher circulating Lp(a) levels

Pavanello, Chiara, Pirazzi, Carlo, Bjorkman, Kristina, Sandstedt, Joakim, Tarlarini, Claudia, Mosca, Lorena, Romeo, Stefano, Calabresi, Laura, Mancina, Rosellina Margherita

Journal:

Journal of Clinical Lipidology

Year:

2019

Language:

english

File:

PDF, 642 KB

english, 2019

2

An Integrated Understanding of the Rapid Metabolic Benefits of a Carbohydrate-Restricted Diet on Hepatic Steatosis in Humans

Mardinoglu, Adil, Wu, Hao, Bjornson, Elias, Zhang, Cheng, Hakkarainen, Antti, Räsänen, Sari M., Lee, Sunjae, Mancina, Rosellina M., Bergentall, Mattias, Pietiläinen, Kirsi H., Söderlund, Sanni, Matika

Journal:

Cell Metabolism

Year:

2018

Language:

english

File:

PDF, 3.62 MB

english, 2018

3

Virtual genetic diagnosis for familial hypercholesterolemia powered by machine learning

Pina, Ana, Helgadottir, Saga, Mancina, Rosellina Margherita, Pavanello, Chiara, Pirazzi, Carlo, Montalcini, Tiziana, Henriques, Roberto, Calabresi, Laura, Wiklund, Olov, Macedo, M Paula, Valenti, Luca

Journal:

European Journal of Preventive Cardiology

Year:

2020

File:

PDF, 524 KB

2020

4

PNPLA3 I148M (rs738409) genetic variant is associated with hepatocellular carcinoma in obese individuals

Maria Antonella Burza, Carlo Pirazzi, Cristina Maglio, Kajsa Sjöholm, Rosellina Margherita Mancina, Per-Arne Svensson, Peter Jacobson, Martin Adiels, Marco Giorgio Baroni, Jan Borén, Stefano Ginanni C

Journal:

Digestive and Liver Disease

Year:

2012

Language:

english

File:

PDF, 210 KB

english, 2012

5

Patatin-like phospholipase domain-containing 3 (PNPLA3) I148M (rs738409) affects hepatic VLDL secretion in humans and in vitro

Pirazzi, Carlo, Adiels, Martin, Burza, Maria Antonella, Mancina, Rosellina Margherita, Levin, Malin, Ståhlman, Marcus, Taskinen, Marja-Riitta, Orho-Melander, Marju, Perman, Jeanna, Pujia, Arturo, Ande

Journal:

Journal of Hepatology

Year:

2012

Language:

english

File:

PDF, 2.51 MB

english, 2012

6

Recombinant PNPLA3 protein shows triglyceride hydrolase activity and its I148M mutation results in loss of function

Pingitore, Piero, Pirazzi, Carlo, Mancina, Rosellina M., Motta, Benedetta M., Indiveri, Cesare, Pujia, Arturo, Montalcini, Tiziana, Hedfalk, Kristina, Romeo, Stefano

Journal:

Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids

Year:

2014

Language:

english

File:

PDF, 440 KB

english, 2014

7

The COBLL1 C allele is associated with lower serum insulin levels and lower insulin resistance in overweight and obese children

Mancina, Rosellina Margherita, Burza, Maria Antonella, Maglio, Cristina, Pirazzi, Carlo, Sentinelli, Federica, Incani, Michela, Montalcini, Tiziana, Pujia, Arturo, Congiu, Tiziana, Loche, Sandro, Pili

Journal:

Diabetes/Metabolism Research and Reviews

Year:

2013

Language:

english

File:

PDF, 96 KB

english, 2013

8

Transmembrane 6 superfamily member 2 gene E167K variant impacts on steatosis and liver damage in chronic hepatitis C patients

Milano, Marta, Aghemo, Alessio, Mancina, Rosellina Margherita, Fischer, Janett, Dongiovanni, Paola, De Nicola, Stella, Fracanzani, Anna Ludovica, D'Ambrosio, Roberta, Maggioni, Marco, De Francesco, Ra

Journal:

Year:

2015

Language:

english

File:

PDF, 208 KB

english, 2015

9

Statin use and non-alcoholic steatohepatitis in at risk individuals

Dongiovanni, Paola, Petta, Salvatore, Mannisto, Ville, Mancina, Rosellina Margherita, Pipitone, Rosaria, Karja, Vesa, Maggioni, Marco, Kakela, Pirjo, Wiklund, Olov, Mozzi, Enrico, Grimaudo, Stefania,

Journal:

Journal of Hepatology

Year:

2015

Language:

english

File:

PDF, 600 KB

english, 2015

10

Paradoxical Dissociation Between Hepatic Fat Content and De Novo Lipogenesis Due to PNPLA3 Sequence Variant

Mancina, Rosellina M., Matikainen, Niina, Maglio, Cristina, Söderlund, Sanni, Lundbom, Nina, Hakkarainen, Antti, Rametta, Raffaela, Mozzi, Enrico, Fargion, Silvia, Valenti, Luca, Romeo, Stefano, Taski

Journal:

Journal of Clinical Endocrinology & Metabolism

Year:

2015

Language:

english

File:

PDF, 284 KB

english, 2015

11

The IRS1 rs2943641 Variant and Risk of Future Cancer Among Morbidly Obese Individuals

Maglio, Cristina, Ericson, Ulrika, Burza, Maria Antonella, Mancina, Rosellina Margherita, Pirazzi, Carlo, Assarsson, Johanna Andersson, Sjöholm, Kajsa, Baroni, Marco Giorgio, Svensson, Per-Arne, Monta

Journal:

Journal of Clinical Endocrinology & Metabolism

Year:

2013

Language:

english

File:

PDF, 227 KB

english, 2013

12

The MBOAT7-TMC4 Variant rs641738 Increases Risk of Nonalcoholic Fatty Liver Disease in Individuals of European Descent

Mancina, Rosellina Margherita, Dongiovanni, Paola, Petta, Salvatore, Pingitore, Piero, Meroni, Marica, Rametta, Raffaela, Borén, Jan, Montalcini, Tiziana, Pujia, Arturo, Wiklund, Olov, Hindy, George,

Journal:

Gastroenterology

Year:

2016

Language:

english

File:

PDF, 1.16 MB

english, 2016

13

DEPDC5 variants increase fibrosis progression in Europeans with chronic hepatitis C virus infection

Burza, Maria Antonella, Motta, Benedetta Maria, Mancina, Rosellina Margherita, Pingitore, Piero, Pirazzi, Carlo, Lepore, Saverio Massimo, Spagnuolo, Rocco, Doldo, Patrizia, Russo, Cristina, Lazzaro, V

Journal:

Year:

2016

Language:

english

File:

PDF, 648 KB

english, 2016

14

Transmembrane-6 superfamily member 2 (TM6SF2) E167K variant increases susceptibility to hepatic steatosis in obese children

Mancina, Rosellina M., Sentinelli, Federica, Incani, Michela, Bertoccini, Laura, Russo, Cristina, Romeo, Stefano, Baroni, Marco G.

Journal:

Digestive and Liver Disease

Year:

2016

Language:

english

File:

PDF, 86 KB

english, 2016

15

Identification and characterization of two novel mutations in the LPL gene causing type I hyperlipoproteinemia

Pingitore, Piero, Lepore, Saverio Massimo, Pirazzi, Carlo, Mancina, Rosellina Margherita, Motta, Benedetta Maria, Valenti, Luca, Berge, Knut Erik, Retterstøl, Kjetil, Leren, Trond P., Wiklund, Olov, R

Journal:

Journal of Clinical Lipidology

Year:

2016

Language:

english

File:

PDF, 966 KB

english, 2016

16

PNPLA3 148M Carriers with Inflammatory Bowel Diseases Have Higher Susceptibility to Hepatic Steatosis and Higher Liver Enzymes

Mancina, Rosellina Margherita, Spagnuolo, Rocco, Milano, Marta, Brogneri, Simona, Morrone, Attilio, Cosco, Cristina, Lazzaro, Veronica, Russo, Cristina, Ferro, Yvelise, Pingitore, Piero, Pujia, Arturo

Journal:

Inflammatory Bowel Diseases

Year:

2016

Language:

english

File:

PDF, 314 KB

english, 2016

17

PNPLA3 overexpression results in reduction of proteins predisposing to fibrosis

Pingitore, Piero, Dongiovanni, Paola, Motta, Benedetta Maria, Meroni, Marica, Lepore, Saverio Massimo, Mancina, Rosellina Margherita, Pelusi, Serena, Russo, Cristina, Caddeo, Andrea, Rossi, Giorgio, M

Journal:

Human Molecular Genetics

Year:

2016

Language:

english

File:

PDF, 1.87 MB

english, 2016

18

Telomerase reverse transcriptase germline mutations and hepatocellular carcinoma in patients with nonalcoholic fatty liver disease

Donati, Benedetta, Pietrelli, Alessandro, Pingitore, Piero, Dongiovanni, Paola, Caddeo, Andrea, Walker, Lucy, Baselli, Guido, Pelusi, Serena, Rosso, Chiara, Vanni, Ester, Daly, Ann, Mancina, Rosellina

Journal:

Cancer Medicine

Year:

2017

Language:

english

File:

PDF, 238 KB

english, 2017

19

Protein phosphatase 1 regulatory subunit 3B gene variation protects against hepatic fat accumulation and fibrosis in individuals at high risk of nonalcoholic fatty liver disease

Dongiovanni, Paola, Meroni, Marica, Mancina, Rosellina M., Baselli, Guido, Rametta, Raffaela, Pelusi, Serena, Männistö, Ville, Fracanzani, Anna L., Badiali, Sara, Miele, Luca, Grimaudo, Stefania, Pett

Journal:

Hepatology Communications

Year:

2018

Language:

english

File:

PDF, 358 KB

english, 2018

20

Deregulation of SGK1 in Ulcerative Colitis: A Paradoxical Relationship Between Immune Cells and Colonic Epithelial Cells

Spagnuolo, Rocco, Dattilo, Vincenzo, D’Antona, Lucia, Cosco, Cristina, Tallerico, Rossana, Ventura, Valeria, Conforti, Francesco, Camastra, Caterina, Mancina, Rosellina M, Catalogna, Giada, Cosco, Vin

Journal:

Inflammatory Bowel Diseases

Year:

2018

Language:

english

File:

PDF, 1.65 MB

english, 2018

21

Pnpla3 silencing with antisense oligonucleotides ameliorates nonalcoholic steatohepatitis and fibrosis in Pnpla3 I148M knock-in mice

Lindén, Daniel, Ahnmark, Andrea, Pingitore, Piero, Ciociola, Ester, Ahlstedt, Ingela, Andréasson, Anne-Christine, Sasidharan, Kavitha, Madeyski-Bengtson, Katja, Zurek, Magdalena, Mancina, Rosellina M.

Journal:

Molecular Metabolism

Year:

2019

File:

PDF, 3.87 MB

2019

22

Pnpla3 silencing with antisense oligonucleotides ameliorates nonalcoholic steatohepatitis and fibrosis in Pnpla3 I148M knock-in mice

Lindén, Daniel, Ahnmark, Andrea, Pingitore, Piero, Ciociola, Ester, Ahlstedt, Ingela, Andréasson, Anne-Christine, Sasidharan, Kavitha, Madeyski-Bengtson, Katja, Zurek, Magdalena, Mancina, Rosellina M.

Journal:

Molecular Metabolism

Year:

2019

Language:

english

File:

PDF, 3.87 MB

english, 2019

23

PCSK7 gene variation bridges atherogenic dyslipidemia with hepatic inflammation in NAFLD patients

Dongiovanni, Paola, Meroni, Marica, Baselli, Guido Alessandro, Mancina, Rosellina M., Ruscica, Massimiliano, Longo, Miriam, Rametta, Raffaela, Cespiati, Annalisa, Pelusi, Serena, Ferri, Nicola, Ranzan

Journal:

The Journal of Lipid Research

Year:

2019

File:

PDF, 1.01 MB

2019

24

High prevalence of genetic determined familial hypercholesterolemia in premature coronary artery disease

Pirazzi, Carlo, Håkansson, Lina, Gustafsson, Carola, Omerovic, Elmir, Wiklund, Olov, Mancina, Rosellina M.

Journal:

The Application of Clinical Genetics

Year:

2019

Language:

english

File:

PDF, 349 KB

english, 2019

25

High prevalence of genetic determined familial hypercholesterolemia in premature coronary artery disease

Pirazzi, Carlo, Håkansson, Lina, Gustafsson, Carola, Omerovic, Elmir, Wiklund, Olov, Mancina, Rosellina M.

Journal:

The Application of Clinical Genetics

Year:

2019

File:

PDF, 349 KB

2019

26

The TM6SF2 E167K genetic variant induces lipid biosynthesis and reduces apolipoprotein B secretion in human hepatic 3D spheroids

Prill, Sebastian, Caddeo, Andrea, Baselli, Guido, Jamialahmadi, Oveis, Dongiovanni, Paola, Rametta, Raffaela, Kanebratt, Kajsa P., Pujia, Arturo, Pingitore, Piero, Mancina, Rosellina Margherita, Lindé

Journal:

Scientific Reports

Year:

2019

Language:

english

File:

PDF, 3.78 MB

english, 2019

27

Natural Extracts as Modifiers of Intracellular Lipid Handling

Mancina, Rosellina Margherita, Pingitore, Piero

Journal:

Annals of Hepatology

Year:

2018

Language:

english

File:

PDF, 198 KB

english, 2018

28

Four-Week Omega-3 Supplementation in Carriers of the Prosteatotic PNPLA3 p.I148M Genetic Variant: An Open-Label Study

Kuttner, Clara-Sophie, Mancina, Rosellina, Wagenpfeil, Gudrun, Lammert, Frank, Stokes, Caroline S.

Journal:

Lifestyle Genomics

Year:

2019

Language:

english

File:

PDF, 274 KB

english, 2019

29

Gastrointestinal Symptoms of and Psychosocial Changes in Inflammatory Bowel Disease: A Nursing-Led Cross-Sectional Study of Patients in Clinical Remission

Mancina, Rosellina Margherita, Pagnotta, Raffaele, Pagliuso, Caterina, Albi, Vincenzo, Bruno, Daniela, Garieri, Pietro, Doldo, Patrizia, Spagnuolo, Rocco

Journal:

Year:

2020

Language:

english

File:

PDF, 1.04 MB

english, 2020

30

LPIAT1/MBOAT7 depletion increases triglyceride synthesis fueled by high phosphatidylinositol turnover

Tanaka, Yuki, Shimanaka, Yuta, Caddeo, Andrea, Kubo, Takuya, Mao, Yanli, Kubota, Tetsuya, Kubota, Naoto, Yamauchi, Toshimasa, Mancina, Rosellina Margherita, Baselli, Guido, Luukkonen, Panu, PihlajamÃ¤

Journal:

Year:

2020

File:

PDF, 2.53 MB

2020

31

Genetic variants in the MTHFR are not associated with fatty liver disease

De Vincentis, Antonio, Mancina, Rosellina Margherita, PhilamajÃ¤ki, Jussi, MÃ¤nnistÃ¶, Ville, Petta, Salvatore, Dongiovanni, Paola, Fracanzani, Anna, Valenti, Luca, Tavaglione, Federica, Romeo, Stefan

Journal:

Liver International

Year:

2020

File:

PDF, 7.05 MB

2020

32

Macrophage scavenger receptor 1 mediates lipid-induced inflammation in human obesity-related non-alcoholic fatty liver disease

Govaere, Olivier, Martinez-Lopez, Nuria, Petersen, Sine K., Mancina, Rosellina, Lassen, Pierre Bel, Darlay, Rebecca, Peltier, Julien, Younes, Ramy, Tiniakos, Dina, Aithal, Guruprasad, Allison, Michael

Journal:

Journal of Hepatology

Year:

2020

File:

PDF, 162 KB

2020

33

Cross talk between liver and adipose tissue: A new role for PNPLA3?

Mancina, Rosellina M., Spagnuolo, Rocco

Journal:

Liver International

Year:

2020

File:

PDF, 771 KB

2020

34

Ulcerative Colitis as an Independent Risk Factor for Hepatic Steatosis

Mancina, Rosellina Margherita, De Bonis, Daniele, Pagnotta, Raffele, Cosco, Cristina, Cosco, Vincenzo, Montalcini, Tiziana, Pujia, Arturo, Doldo, Patrizia, Spagnuolo, Rocco

Journal:

Gastroenterology Nursing

Year:

2020

File:

PDF, 346 KB

2020

35

PCSK9 rs11591147 R46L LossâofâFunction Variant Protects Against Liver Damage in Individuals with NAFLD

Grimaudo, Stefania, Bartesaghi, Stefano, Rametta, Raffaela, Marra, Fabio, Mancina, Rosellina Margherita, PihlajamÃ¤ki, Jussi, KakolâPalm, Dorota, AndrÃ©asson, AnneâChristine, Dongiovanni, Paola, F

Journal:

Liver International

Year:

2020

File:

PDF, 1.46 MB

2020

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